The infectious hepatitis vaccine is a MLV vaccine containing CAV-2. This vaccine protects against canine hepatitis and two of the adenoviruses involved in the kennel cough complex (CAV-1 and CAV-2).
Hepatitis vaccine is incorporated into the DHPP shot, which is given at 8 to 12 weeks of age and again at 16 weeks of age with a possible booster in between for puppies who were initially vaccinated at 8 weeks of age or younger. It is suggested that a DHPP booster be given at 1 year of age or one year from the last vaccine. Revaccination is currently recommended every three years, although initial immunity may persist for life.