Erythema multiforme is an acute eruption of the skin and mucous membranes. The characteristic skin lesion is a round or oval target like skin eruption with a red rim and central blanching. There is an association with drugs, infections, tumors, and connective tissue diseases. Erythema multiforme tends to be less severe than toxic epidermal necrolysis.
Treatment: Many cases recover spontaneously, especially if the predisposing cause can be found and corrected. Immunosuppressive medications and corticosteroids may be needed.