Note that many drugs are passed on to puppies in the mother’s milk. The amount depends on the blood concentration and whether the drug is soluble in fat. Fat-soluble drugs are stored in body fat and will be secreted in the milk for prolonged periods. Keep in mind that a newborn’s liver and kidneys are immature and cannot detoxify and eliminate drugs as readily as those of an adult. Avoid giving the dam any drugs during lactation, unless they are prescribed by your veterinarian.